akharris@bio.unc.edu
office phone 966-1230
home 493-1572
Teaching assistants: Marta Szmacinski and Amanda Whitlock
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Summer office hours by appointment at whatever time you and I can arrange. Just tell me some times that are convenient for you, and let me choose among them.
Textbook: "Principles of Development" Lewis Wolpert and Cheryll Tickle Fourth Edition, Oxford U. Press |
| 1) Mon. Jan 9 | Sea Urchin (pp. 233-243) Frog and Mammal Development (Chapter 3 pp. 93-100; lecture notes |
| 2) Wed. Jan 11 | Bird and Teleost Development; (Chapter 3; pp 100-113); lecture notes |
| 3) Fri. Jan 13 | Gastrulation. Formation of Body Axes. Ectoderm, Mesoderm, Endoderm (Chapter 4) |
| Mon. Jan 16 | Holiday |
| 4) Wed. Jan 18 | Extraembryonic Membranes; Three different mechanisms of identical twinning. |
| 5) Fri. Jan. 20 | The many different kinds of symmetry. Mechanisms for becoming LESS symmetrical ( lecture notes) |
| lecture notes on positional information | |
| lecture notes on formation of germ layers updated 1/26/12 | |
| lecture notes on the "French flag" problem | |
| lecture notes on formation of differentiated cell types | |
| diagram of morphogenetic cell movements | |
| 6) Mon. Jan. 23 | Experimental Embryology, Historical advances in concepts (Chapter 1: Pages 1-34) |
| notes on regulative and mosaic development, and some history | |
| 7) Wed. Jan. 25 | Nervous System (Chapter 5: Pages 173-214) |
| 8) Fri. Jan. 27 | Nervous System (Chapter 5: Pages 173-214) |
| 9) Mon. Jan. 30 | Somites (Chapter 5: Pages 173-214) |
| REVIEW QUESTIONS FOR FIRST EXAM | |
| Biology 441 study group: search Facebook for UNC BIOL441 | |
| 10) Wed. Feb. 1 | FIRST EXAMINATION |
| 11) Fri. Feb. 3 | Morphogenesis and Mechanics (Chapter 8: Pages 289-328) |
| lecture notes on reaction-diffusion systems | |
| 12) Mon. Feb. 6 | Morphogenesis and Mechanics (Chapter 8: Pages 289-328) |
| lecture notes on Holy Grails and Riddles of the Sphinx | |
| lecture notes on computer simulations | |
| Dictyostelium video by John Tyler Bonner | |
| 13) Wed. Feb. 8 | |
| 14) Fri. Feb. 10 | Ectoderm lecture notes |
| 15) Mon. Feb. 13 | |
| 16) Wed. Feb. 15 | Somatic ectoderm lecture notes |
| a diversion on Hans Driesch | |
| ship in a bottle | |
| another slime mold video | |
| some links about feather germs and other recent topics | |
| 17) Fri. Feb. 17 | |
| 18) Mon. Feb. 20 | Mesoderm and Endoderm |
| links to some videos showing somite formation and other aspects of development | |
| explanations of somite formation | |
| 19) Wed. Feb. 22 | Heart Development, Kidneys lecture notes |
| 20) Fri. Feb. 24 | Hox Gene Transcription Patterns |
| 21) Mon. Feb. 27 | Plant Development (Chapter 7, pp. 255-258) |
| background on cellular automata, for this week's lab sessions Cell Automata Java program |
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| review questions for second exam (more were added on March 6th and March 8th. also on March 16th) | |
| figures to review for second exam | |
| 22) Wed. Feb. 29 | Plant Development (Chapter 7, pp. 255-258) |
| 23) Fri. Mar. 2 | Plant Development lecture notes - - added March 15 |
| SPRING BREAK | |
| 24) Mon. Mar. 12 | Bioengineering lecture notes |
| 25) Wed. Mar. 14 | Bioengineering |
| 26) Fri. Mar. 16 | Bioengineering web page: Electroosmosis Causes Cartilage to Expand |
| A few more notes on tensors, in relation to cartilage formation and other things | |
| 27) Mon. Mar. 19 | SECOND EXAMINATION |
| 28) Wed. Mar. 21 | Cartilage images of cartilage, collagen, arteries |
| 29) Fri. Mar. 23 | Bone lecture notes |
| 30) Mon. Mar. 26 | Nerve axon guidance and specificity of connection images and notes - more text was added March 27th |
| 31) Wed. Mar. 28 | Nerve axon guidance and specificity of connection |
| 32) Fri. Mar. 30 | Nerve axon guidance and specificity of connection |
| 33) Mon. Apr. 2 | Limb bud development |
| 34) Wed. Apr. 4 | Limb development lecture notes |
| Fri. Apr. 6 | Good Friday Holiday |
| review questions for third exam | |
| 35) Mon. Apr. 9 | Limb development |
| 36) Wed. Apr. 11 | THIRD EXAMINATION |
| 37) Fri. Apr. 13 | Cell differentiation and stem cells lecture notes |
| 38) Mon. Apr. 16 | Metamorphosis (Chapter 13: Pages 505-534; lecture notes) |
| 39) Wed. Apr. 18 | Aging (Chapter 13: Pages 505-534; additional figures) |
| 40) Fri. Apr. 20 | Development of the immune system; autoimmune diseases (Chapter 15; lecture notes) |
| 41) Mon. Apr. 23 | Evolution and Development (Chapter 15: Pages 556-585) |
| 42) Wed. Apr. 25 | Cancer: A breakdown of embryological mechanisms (Chapter 15: Pages 556-585; lecture notes ) |
review questions since third exam - the list is now complete |
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| Wednesday 3:30 pm: a statement about exam content and grading has been added to this list of review questions. | |
| Friday April 27 | FINAL EXAM 8:00 A.M. ! |