Syllabus  Biology 441 Vertebrate Embryology  Albert Harris    Spring 2018

MWF 9:05-9:55 Wilson 107

Office: Room 103 Wilson Hall
Office Hours: 10-12 Monday and Wednesday, or at other times by appointment

e-mail: akharris@bio.unc.edu
web sites: http://www. albertkharris.com and http://www.bio.unc.edu/faculty/harris/

office phone 919-966-1230
home 919-493-1572

Teaching assistants: Lindsay Wickersham and Chris Cunningham

 

Lecture notes, videos, review questions, and other material needed for exams will be posted on this web site throughout the semester.
Please check it frequently for updates.

The Biology 441L lab is NOT required for students taking the lecture course. It is a separate 1-hour course.    revised lab syllabus
Labs will begin on January 24-25.
 

exams and grading

  
1) Wed. Jan 10 Mammal Embryology in Contrast with Sea Urchin Embryology
lecture notes
 
2) Friday Jan 12 Subdivision of Vertebrate Embryos into Ectoderm, Mesoderm & Endoderm
lecture notes
 
 
    Monday Jan 15 ******* Holiday in Honor of Martin Luther King Jr. ********
 
3) Wednesday Jan 17 snow day
 
4) Friday Jan 19 snow day
 
 
 
5) Monday Jan 22 Morphogenetic Movements and Shape Formation
lecture notes
 
6) Wednesday Jan 24 Amoeboid locomotion, Electro-osmosis and Fluid-filled Spaces
lecture notes
 
7) Friday Jan 26 Fish and Amphibian Embryology
drawing of early development in vertebrate embryos
lecture notes

 
 
8) Monday Jan 29 Embryology of Birds and Mammals; Extra-embryonic Membranes
lecture notes
 
9) Wednesday Jan 31 Regulative vs. Mosaic Development, Experimental Embryology
lecture notes
 
10) Friday Feb 2 Review for first examination, followed by office hours
review questions
 
 
11) Monday Feb 5 First Examination
 
12) Wednesday Feb 7 Some Mathematical Concepts that Are Needed to Understand Shape Formation:
Pressures, Surface Curvatures, and Tensions
lecture notes
 
13) Friday Feb 9 How Do Physical Forces Cause the Shapes of Anatomical Structures?
lecture notes continued from Wednesday

 
 
14) Monday Feb 12 Symmetries of Causes Control Symmetries of Anatomical Shapes
lecture notes

 
15) Wednesday Feb 14 Reaction-Diffusion Systems: Instabilities that Create Geometric Patterns
lecture notes

 
16) Friday Feb 16 Somites and Other Structures that Develop From Mesoderm
lecture notes

 
 
17) Monday Feb 19 Ovaries and Testes; Primordial Germ Cells and Gamete Formation
See the last part of the notes for Friday.
Ectoderm: lecture notes
A picture showing early neurulation was added to this page 2/25/18, 7 pm

 
18) Wednesday Feb 21 Retino-tectal projections: lecture notes

 
19) Friday Feb 23 Chemotaxis: lecture notes
Stomodeum and Endoderm: lecture notes
 
 
20) Monday Feb 26 Review for Second Examination, followed by office hours
first set of review questions
second set

 
21) Wednesday Feb 28 Heart Development, Guest Lecture by Chris Cunningham
The video links that were mentioned in the lecture:
classic animation used in medical school teaching
heart embryology animation using Claymation
downloadable Powerpoint file
 
22) Friday Mar 2 Second Examination
 
 
23) Monday Mar 5 Sponge Aggregation and Cell Sorting
lecture notes
 
24) Wednesday Mar 7 Lessons from the History of Cell Sorting; Beginning Limb Buds
lecture notes
 
25) Friday Mar 9 Limb Buds
lecture notes
 
 
 March 12-16 spring break
 
 
26) Monday Mar 19 Programmed Cell Death
lecture notes
 
27) Wednesday Mar 21 More on Limb Buds, the Apical Epidermal Ridge, and Regeneration
lecture notes
 
28) Friday Mar 23 Liesegang Rings   lecture notes
Atherosclerosis   lecture notes
a YouTube video on regeneration in axolotls
 
 
29) Monday Mar 26 Immunology, Allergies, and Autoimmune Diseases in Relation to Embryology
lecture notes
 
30) Wednesday Mar 28 Immunology, continued
 
      Friday March 30 ******* Holiday ********
 
 
32) Monday Apr 2 More on Immunology
 
33) Wednesday Apr 4 Review for Third Examination
first set of review questions
second set of review questions
third set of review questions

YouTube video of chick embryo development (not required, but you might find it interesting)

 
34) Friday Apr 6 Third Examination
 
 
35) Monday Apr 9 Embryology of Plants
lecture notes
 
36) Wednesday Apr 11 Resting Potentials, Fertilization, and Galvanotaxis
lecture notes
 
36) Friday Apr 13 Continuation of Wednesday's topic, then begin metamorphosis
lecture notes
 
 
37) Monday Apr 16 Metamorphosis
lecture notes
 
38) Wednesday Apr 18 Aging
lecture notes
some links on cellular automata; will be discussed next week
 
39) Friday Apr 20 Cancer
 
 
40) Monday Apr 23 Cancer, continued
lecture notes
[same information that was posted Friday, but re-ordered and lightly edited]
 
41) Wednesday Apr 25
 
42) Friday Apr 27
 
 
 
  FINAL EXAM: Monday, May 7, 8:00 am